Gaucher Disease Write for Us
Gaucher Disease Write for Us – Gaucher disease (go-SHAY) results from the buildup of certain fatty substances in specific organs, particularly the spleen, and liver. This causes these organs to swell and can affect their function.
Fatty substances can also build up and increase the risk of fractures by causing changes in bone tissue. If the afflicted bone marrow, it may interfere with the blood’s ability to clot.
In persons with Gaucher disease, the enzyme that breaks down these fatty compounds does not function properly. Enzyme replacement therapy is frequently used during treatment. Gaucher disease is a genetic disorder, and it is most common among Jews of Eastern and Central European (Ashkenazi) descent. Symptoms can appear at any age.
What Causes Gaucher Disease?
Gaucher disease is passed from parents to children (inherited). A problem with the GBA gene causes it.
This condition is autosomal recessive. A parent must pass on a faulty GBA gene to their offspring to get Gaucher. The parents may only carry one GBA gene, preventing them from developing the illness but still making them carriers. Jews of Ashkenazi descent are most frequently affected by type 1 Gaucher disease caused by a faulty GBA gene. What are the symptoms of Gaucher disease?
Each person’s symptoms may be different. For many people, symptoms begin in childhood. Some people have very mild symptoms.
Symptoms of Gaucher disease can include:
- splenomegaly
- Hepatomegaly
- Eye movement disorders
- Yellow spots in the eye
- Extreme exhaustion (fatigue), anemia (lack of healthy red blood cells), and other conditions rises
- Lung problems
- seizures
How is Gaucher’s disease diagnosed?
Your healthcare provider will look at your general and past health to diagnose. They will perform a physical examination.
Your provider will also consider the following:
- Your description of the symptoms
- Your family medical history
- Blood test results
Because there are so many symptoms of Gaucher disease, it can take time to get an accurate diagnosis.
How is Gaucher Disease Treated?
The illness Gaucher has no known treatment. However, medication might assist you in managing your symptoms. Your treatment will depend on the type of Gaucher disease you have. Treatment may include:
- Enzyme replacement therapy, which is effective in types 1 and 3
- pharmaceutical
- Regular physical exams and bone density checks to check for your disease
- Bone marrow transplant
- Surgery to remove all or part of the spleen
- Joint replacement surgery
- Transfusion
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